CoQ-10 (Ubiquinone) with Vitamin A Serum
A potent combination to regenerate sun-damaged skin. Suitable for sensitive skin.
CoQ-10 is well known as a powerful antioxidant (and dietary supplement), but it really excels in topical use, partly due to being lipophilic. Where other ant-oxidants need help getting through the waxy surface of the epidermis, this does it smoothly, without irritating. The right concentration is important for it to be effective and combining it with vitamin A (retinol palmitate - a less irritating alternative to retinol), maximises the bioavailability of CoQ-10. Together these protect from UVA and UVB oxidative damage and mitigate the deterioration of glutamine in the skin. CoQ-10 has increased elastin and collagen (type 1 and IV) production in in-vitro and in-vivo trials. We include niacinamide, to help it restore skin-damage, dampen inflammation and stimulate fibroblast proliferation and renewal.
The moisturising effect is comprehensively covered by hyaluronic acid and sodium hyaluronate, botanical extracts, panthenol and soy lecithin. These provide thorough skin-moisturisation, whilst squalane and vitamin E help optimise the skin’s barrier lipids. Well hydrated skin should see slower degradation of collagen and prevent the clumps of sticky, dead cells forming on the surface. This then allows the effective ingredients to get in to where they need to be. Reversing damage takes time, but a smoother texture should be noticeable after a few days. As depleted stores are restored, skin feels thicker and is better able to repair. Can cause sun sensitivity.
Directions for Use:
Use a pea-sized amount to fingertips and apply in circular, upward movements (neck to forehead) to cleansed skin. Allow it to be absorbed for five minutes before using another serum, elixir or moisturiser. If using other serums, apply this first (the lipophilic nature of CoQ-10 primes the skin.) If using this and the Copper Peptide serum, oily skin may respond better to using this second; for dry skin, apply this first. To counter increased sun sensitivity, use a broad-spectrum sun cream.
CoQ-10 and Vitamin A Serum - Academic research
Yukitoshi Mine et al; Nov 2021; Protective effects of coenzyme Q10 on cell damage
Zasada et al; Aug 2019 - Vitamin A influencing skin structure
Hseu et al; Jun 2019 -Aantioxidant and depigmenting melasma - Coenzyme Q10
Baumann, 2015 - Collagen production
Oliveira et al; 2014 Retinyl Palmitate…for the Treatment of Skin Aging
Chang et al, 2012 Fibroblast production
Zhou et al; 2010 - Lecithin-Based Coenzyme Q10-Loaded Lipid Nanocapsules
Serri, Iorizzo; 2008 - Topical retinoids in photoaging
Sorg et al; 2005 - Skin ageing
Glaser - 2004 - Retinyl palmitate anti-aging
Ingredients: Rose Damascene distilled flower water; Oenothera biennis flower water; Calendula distilled flower water; Glycerin; Decyl oleate; Squalane; Coenzyme Q10; Retinyl palmitate; Soy lecithin; Chamaemelum nobile extract; Niacinamide; Urea; Lactic acid, Panthenol; Calendula flower extract; Cetearyl alcohol; Isoamyl Laurate; Oenothera biennis extract; Cyclomethicone; Glyceryl stearate; Tocopherol; Argania Spinosa kernel oil; Rosa canina fruit oil, Sclerocarya birrea seed oil; Polysorbate 80; Hyaluronic acid; Colloidal oats; Xanthan gum; phenoxyethanol & caprylyl glycol; Sodium hyaluronate; Zinc oxide; Allantoin; Triethanolamine. Cymbopogon martinii oil; Commiphora myrrha resin extract; Vetiveria zizanoides root oil; Pelargonium graveolens flower oil; Boswellia carterii oleoresin; Jasminum sambac absolute; Sandal pentanol; Rosa centifolia absolute; Phenyl ethyl alcohol; Limonene; Citronellol; Linalool; Benzyl acetate; Geraniol; Geranyl acetate; Linalyl Acetate; Benzyl benzoate.